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Optical coherence tomography (OCT)

Leader: Bernhard Baumann

Optical coherence tomography (OCT) is an optical technology for real-time and high-resolution imaging. At MUI’s Institute of Biomedical Physics, we are developing novel methods for OCT imaging with additional contrast, ultrahigh resolution, and ultrahigh speed. In close collaborations with partners in basic research and clinical medicine, we exploit OCT for non-invasive imaging in biomedical applications.

  • Georg Ladurner, Danielle J. Harper, Lucas May, Sybren Worm, Yash Patel, Maria Varaka, Manuela Prokesch, Gerhard Garhöfer, Conrad Merkle, Bernhard Baumann; Comparative Investigation of the Retinal Phenotype of Three Mouse Models of Alzheimer’s Disease With Optical Coherence Tomography. Investigative Ophthalmology & Visual Science 66(14), 35 (2025). https://doi.org/10.1167/iovs.66.14.35
  • Lucas May, Sybren Worm, Maria Varaka, Georg Ladurner, Yash Patel, Antonia Lichtenegger, Sarah Nagl, Andreas Drauschke, Conrad Merkle, Ireneusz Grulkowski, and Bernhard Baumann, “Analysis of pulsatile motion in the murine cornea using phase-sensitive visible-light optical coherence tomography,” Biomedical Optics Express 16, 3510-3523 (2025). https://doi.org/10.1364/BOE.565471
  • Kim Lien Huber,  Heiko Stino,  Thomas Schlegl,  Irene Steiner,  Gergely Nagy,  Michael Niederleithner,  Bernhard Baumann,  Wolfgang Drexler,  Rainer A. Leitgeb,  Ursula Schmidt-Erfurth,  Tilman Schmoll,  and Andreas Pollreisz, “Microaneurysm detection using high-speed megahertz optical coherence tomography angiography in advanced diabetic retinopathy,” Acta Ophthalmologica, 102, e687–e695 (2024). https://doi.org/10.1111/aos.16619
  • Mia Kvåle Løvmo, Shiyu Deng, Simon Moser, Rainer Leitgeb, Wolfgang Drexler, and Monika Ritsch-Marte, “Ultrasound-induced reorientation for multi-angle optical coherence tomography,” Nature Communications 15, 2391 (2024). https://doi.org/10.1038/s41467-024-46506-2